Integrated physiologic assessment of ischemic heart disease in real-world practice using index of microcirculatory resistance and fractional flow reserve: insights from the International Index of Microcirculatory Resistance Registry.

@article{Lee2015IntegratedPA,
  title={Integrated physiologic assessment of ischemic heart disease in real-world practice using index of microcirculatory resistance and fractional flow reserve: insights from the International Index of Microcirculatory Resistance Registry.},
  author={Joo Myung Lee and Jamie Layland and Ji-Hyun Jung and Hyun-Jeong Lee and Mauro Echavarr{\'i}a-Pinto and Stuart Watkins and Andy S. C. Yong and Joon-Hyung Doh and C J Nam and Eun Seok Shin and Bon Kwon Koo and Martin K. C. Ng and Javier Escaned and William Fuller Fearon and Keith G Oldroyd},
  journal={Circulation. Cardiovascular interventions},
  year={2015},
  volume={8 11},
  pages={e002857}
}
BACKGROUND The index of microcirculatory resistance (IMR) is a quantitative and specific index for coronary microcirculation. However, the distribution and determinants of IMR have not been fully investigated in patients with ischemic heart disease (IHD). METHODS AND RESULTS Consecutive patients who underwent elective measurement of both fractional flow reserve (FFR) and IMR were enrolled from 8 centers in 5 countries. Patients with acute myocardial infarction were excluded. To adjust for the… CONTINUE READING