Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells

@article{Chaumeil2002IntegratedKO,
  title={Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells},
  author={J. Chaumeil and I. Okamoto and M. Guggiari and E. Heard},
  journal={Cytogenetic and Genome Research},
  year={2002},
  volume={99},
  pages={75 - 84}
}
  • J. Chaumeil, I. Okamoto, +1 author E. Heard
  • Published 2002
  • Medicine, Biology
  • Cytogenetic and Genome Research
  • Inactivation of the X chromosome during early female development and the subsequent maintenance of this transcriptionally inert state through countless cell divisions remain a paradigm for epigenetic regulation in mammals. Nevertheless, the exact mechanisms underlying this chromosome-wide silencing process remain unclear. Using differentiating female embryonic stem (ES) cells as a model system, we recently found that histone H3 tail modifications are among the earliest known chromatin changes… CONTINUE READING
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    • 134
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    • 63
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    • E. Heard
    • Biology, Medicine
    • Current opinion in cell biology
    • 2004
    • 293
    • PDF
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    • 148
    • PDF
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    • 28
    • PDF
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    • 89
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    • 20

    References

    SHOWING 1-10 OF 56 REFERENCES
    X-Inactivation and histone H4 acetylation in embryonic stem cells.
    • 254
    • Highly Influential
    • PDF
    Xist RNA and the mechanism of X chromosome inactivation.
    • 414
    • PDF
    Histone H3 Lysine 9 Methylation Occurs Rapidly at the Onset of Random X Chromosome Inactivation
    • 173
    • Highly Influential
    • PDF
    Imprinted X inactivation maintained by a mouse Polycomb group gene
    • 316
    Correlation between X-chromosome inactivation and cell differentiation in female preimplantation mouse embryos.
    • 44
    Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation
    • 337
    Methylation of Histone H3 at Lys-9 Is an Early Mark on the X Chromosome during X Inactivation
    • 498