Integrated interactions between chondroitin sulphate proteoglycans and weak dc electric fields regulate nerve growth cone guidance in vitro.

@article{Erskine1997IntegratedIB,
  title={Integrated interactions between chondroitin sulphate proteoglycans and weak dc electric fields regulate nerve growth cone guidance in vitro.},
  author={Lynda Erskine and Colin D. McCaig},
  journal={Journal of cell science},
  year={1997},
  volume={110 ( Pt 16)},
  pages={1957-65}
}
During development and regenerative growth, neuronal pathways are defined in part by several endogenous cues that collectively determine directed growth. The interactions between such cues largely are unknown. To address potential interactions, we have examined in vitro the combined effect on nerve growth of two endogenous growth cone guidance cues: chondroitin sulphate proteoglycans and weak dc electric fields. Addition to the culture medium of a chondroitin 6-sulphate/keratan sulphate… CONTINUE READING
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