Integrated in vivo pharmacology using an instrumented, unrestrained and conscious rat platform: application to rat models of diabetes.

Abstract

INTRODUCTION We define the technical and methodological aspects that led to a practical and reproducible biological in vivo platform allowing the measurement of more than 65 physiobiochemical parameters on a daily basis in freely moving conscious animals. Such a platform presents the ability to unleash incremental information in the hands of modern-day… (More)

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@article{Nantel2006IntegratedIV, title={Integrated in vivo pharmacology using an instrumented, unrestrained and conscious rat platform: application to rat models of diabetes.}, author={François Nantel and Philippe Daull and Nathalie Berthiaume and Dana-Nicoleta Duta and Andr{\'e} Blouin and Julie Cayer and Myriam Beaudoin and Karine Belleville and Ouhida Benrezzak and Pierre Sirois and Bruno Battistini}, journal={Journal of pharmacological and toxicological methods}, year={2006}, volume={53 3}, pages={248-55} }