Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients.

Abstract

Breast cancer is a heterogeneous disease for which alterations in DNA methylation patterns have been shown to be of biological and clinical importance. Here we report on the integrated analysis of molecular alterations including the methylation status of 27 gene promoters analyzed by highly quantitative pyrosequencing, and the association to gene expression… (More)
DOI: 10.1002/ijc.28606

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@article{Fleischer2014IntegratedAO, title={Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients.}, author={Thomas Fleischer and Hege Edvardsen and Hiroko K. Solvang and Christian Daviaud and Bj\orn Naume and Anne-Lise B\orresen-Dale and Vessela N. Kristensen and J{\"{o}rg Tost}, journal={International journal of cancer}, year={2014}, volume={134 11}, pages={2615-25} }