Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model.

Abstract

BACKGROUND The metabolic preference of malignant glioma for glycolysis as an energy source is a potential therapeutic target. As a result of the cellular heterogeneity of these tumors, however, the relation between glycolytic preference, tumor formation, and tumor cell clonogenicity has remained unknown. To address this issue, we analyzed the metabolic… (More)
DOI: 10.1093/neuonc/nou096

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@article{Saga2014IntegratedAI, title={Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model.}, author={Isako Saga and Shunsuke Shibao and Jun Okubo and Satoru Osuka and Yusuke Kobayashi and S Yamada and Satoshi Fujita and Kenichi Urakami and Masatoshi Kusuhara and Kazunari Yoshida and Hideyuki Saya and Oltea Sampetrean}, journal={Neuro-oncology}, year={2014}, volume={16 8}, pages={1048-56} }