Integrated Proteomic Analysis of Human Cancer Cells and Plasma from Tumor Bearing Mice for Ovarian Cancer Biomarker Discovery

@inproceedings{Pitteri2009IntegratedPA,
  title={Integrated Proteomic Analysis of Human Cancer Cells and Plasma from Tumor Bearing Mice for Ovarian Cancer Biomarker Discovery},
  author={Sharon J Pitteri and Lellean JeBailey and Vitor Marcel Faça and Jason Thorpe and Melissa Andreia de Moraes Silva and Renee C Ireton and Marc B. Horton and Hong Wang and Liese C C Pruitt and Qing Zhang and Kuang H. Cheng and Nicole Urban and Samir M Hanash and Daniela M. Dinulescu},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND The complexity of the human plasma proteome represents a substantial challenge for biomarker discovery. Proteomic analysis of genetically engineered mouse models of cancer and isolated cancer cells and cell lines provide alternative methods for identification of potential cancer markers that would be detectable in human blood using sensitive… CONTINUE READING