Integrated Analysis of Microarray Data of Atherosclerotic Plaques: Modulation of the Ubiquitin-Proteasome System

@article{Wang2014IntegratedAO,
  title={Integrated Analysis of Microarray Data of Atherosclerotic Plaques: Modulation of the Ubiquitin-Proteasome System},
  author={Zhe Wang and D. Guo and B. Yang and J. Wang and R. Wang and X. Wang and Qunye Zhang},
  journal={PLoS ONE},
  year={2014},
  volume={9}
}
  • Zhe Wang, D. Guo, +4 authors Qunye Zhang
  • Published 2014
  • Biology, Medicine
  • PLoS ONE
  • Atherosclerosis is a typical complex multi-factorial disease and many molecules at different levels and pathways were involved in its development. Some studies have investigated the dysregulation in atherosclerosis at mRNA, miRNA or DNA methylation level, respectively. However, to our knowledge, the studies that integrated these data and revealed the abnormal networks of atherosclerosis have not been reported. Using microarray technology, we analyzed the omics data in atherosclerosis at mRNA… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Dysfunction of the ubiquitin-proteasome system in atherosclerotic cardiovascular disease.
    • 21
    • Highly Influenced
    • PDF
    Ageing induced vascular smooth muscle cell senescence in atherosclerosis
    • 51
    Macromolecular Degradation Systems and Cardiovascular Aging.
    • 27
    • PDF
    The Role of Defective Macrophage Efferocytosis During Early Atherosclerosis in Humans

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 52 REFERENCES
    Dysregulation of the Ubiquitin-Proteasome System in Human Carotid Atherosclerosis
    • 98
    The Role of p53 in Atherosclerosis
    • 63
    • PDF
    Methylation of FOXP3 in regulatory T cells is related to the severity of coronary artery disease.
    • 54
    The growing role of gene methylation on endocrine function.
    • 30
    • PDF