Integral membrane glycoproteins related to cell-substratum adhesion in mammalian cells.


Broad spectrum antisera have been raised against surface membrane-derived material from baby hamster kidney cells and mouse mammary tumor epithelial cells. These antisera disrupt cell-substratum adhesion in their respective cell types. Using an antibody neutralization (blocking) assay, adhesion-related glycoproteins have been isolated from non-ionic… (More)


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