Intake of trans fatty acids and risk of coronary heart disease among women

@article{Willett1993IntakeOT,
  title={Intake of trans fatty acids and risk of coronary heart disease among women},
  author={Walter C Willett and MeirJ. Stampfer and JoAnn E. Manson and Graham A Colditz and FrankE. Speizer and Bernard A Rosner and Laura Sampson and Charles H Hennekens},
  journal={The Lancet},
  year={1993},
  volume={341},
  pages={581-585}
}
Trans isomers of fatty acids, formed by the partial hydrogenation of vegetable oils to produce margarine and vegetable shortening, increase the ratio of plasma low-density-lipoprotein to high-density-lipoprotein cholesterol, so it is possible that they adversely influence risk of coronary heart disease (CHD). To investigate this possibility, we studied dietary data from participants in the Nurses' Health Study. We calculated intake of trans fatty acids from dietary questionnaires completed by… CONTINUE READING
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