Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise.

@article{Bukhari2015IntakeOL,
  title={Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise.},
  author={Syed Shahid Imran Bukhari and Bethan E. Phillips and Daniel James Wilkinson and Marie C. Limb and Debbie Rankin and William Kyle Mitchell and Hisamine Kobayashi and Paul L Greenhaff and Kenneth G C Smith and Philip J Atherton},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2015},
  volume={308 12},
  pages={E1056-65}
}
Dysregulated anabolic responses to nutrition/exercise may contribute to sarcopenia; however, these characteristics are poorly defined in female populations. We determined the effects of two feeding regimes in older women (66 ± 2.5 yr; n = 8/group): bolus whey protein (WP-20 g) or novel low-dose leucine-enriched essential amino acids (EAA) [LEAA; 3 g (40% leucine)]. Using [(13)C6]phenylalanine infusions, we quantified muscle (MPS) and albumin (APS) protein synthesis at baseline and in response… CONTINUE READING
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