Intake of Fish Oil Specifically Modulates Colonic Muc2 Expression in Middle‐Aged Rats by Suppressing the Glycosylation Process

@inproceedings{Ma2018IntakeOF,
  title={Intake of Fish Oil Specifically Modulates Colonic Muc2 Expression in Middle‐Aged Rats by Suppressing the Glycosylation Process},
  author={Yafang Ma and Guanghong Zhou and Yingqiu Li and Yingying Zhu and Xiaobo Yu and Fan Zhao and He Li and Xinglian Xu and Chunbao Li},
  booktitle={Molecular nutrition & food research},
  year={2018}
}
SCOPE Dietary fats have been shown to affect gut microbiota composition and aging gene expression of middle-aged rats at a normal dose, but little is known about such an effect on gut barrier. In this study, the changes in colonic Muc2 expression are investigated and the underlying mechanism is also proposed. METHODS AND RESULTS 36 middle-aged Sprague-Dawley rats are assigned to one of the diets containing soybean oil, lard, or fish oil (4%). The rats are fed for 5 weeks and then goblet cells… CONTINUE READING
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