Intake and Metabolism of Fluoride

@article{Whitford1994IntakeAM,
  title={Intake and Metabolism of Fluoride},
  author={Gary Milton Whitford},
  journal={Advances in Dental Research},
  year={1994},
  volume={8},
  pages={14 - 5}
}
  • G. Whitford
  • Published 1 June 1994
  • Medicine
  • Advances in Dental Research
The purpose of this paper is to discuss the major factors that determine the body burden of inorganic fluoride. Fluoride intake 25 or more years ago was determined mainly by measurement of the concentration of the ion in the drinking water supply. This is not necessarily true today because of ingestion from fluoride-containing dental products, the "halo effect", the consumption of bottled water, and the use of water purification systems in the home. Therefore, the concentration of fluoride in… 

Figures and Tables from this paper

Fluoride Intake , Metabolism and Toxicity
TLDR
It can be inferred therefore that the human organism is broadly exposed to fluoride, and plasma fluoride levels are not homeostatically regulated and vary according to the levels of intake, deposition in hard tissues and excretion of fluoride.
Fluoride Kinetics and Metabolism
TLDR
The placenta appears to protect the fetus from the toxic effects of fluoride as evident from low transplacental fluoride passage in many animal species and may act as bioindicators of the fluoride burden in animals.
Renal excretion of fluoride after fluoride mouth rinses in children.
TLDR
After the use of a fluoride mouthwash, in children, there is a statistically significant increase of fluoride ion in urine, which can be attributed to the application of this product.
Fluoride and oxidative stress in postmenopausal women
–Fluorosis is a serious public health problem in many parts of the world where drinking water contains more than 1 ppm of fluoride. Higher intake of fluoride will result in dental and skeletal
Impact of water filters and consumption of bottled water on fluoride intake
TLDR
The use of filters and consumption of bottled water were sparse with no significant impact on FH2O over a two-day study period.
Fluoride and environmental health: a review
TLDR
Although much is known about the occurrence and health effects of fluoride, problems persist in Third World countries, where populations have little choice in the source of their drinking water and food, even in developed nations, fluoride ingestion can exceed the recommended dose when sources other than drinking water are ignored.
Fluoride and Environmental Health
TLDR
Although much is known about the occurrence and health effects of fluoride, problems persist in Third World countries, where populations have little choice in the source of their drinking water and food, even in developed nations, fluoride ingestion can exceed the recommended dose when sources other than drinking water are ignored.
[Demonstration of fluoride systemic absorption secondary to toothbrushing with fluoride dentifrice in children].
TLDR
The use of fluoride dentifrice is related to a significant increase of the fluoride concentration in urine in children.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 74 REFERENCES
Serum inorganic fluoride: changes related to previous fluoride intake, renal function and bone resorption.
TLDR
The sensitivity of the serum fluoride concentration to previous intake, glomerular filtration and the intensity of bone resorption suggests that the human organism exerts no direct homeostatic control over this ion.
Topical Fluorides: Effects on Physiologic and Biochemical Processes
TLDR
There is an immediate need for the dissemination to the dental profession of standardized methods for gel application that will minimize the quantities of fluoride available for ingestion and systemic absorption.
Fluoride Intake from Beverage Consumption in a Sample of North Carolina Children
TLDR
The purpose of this study was to estimate the amount of fluoride ingested from beverages by a sample of North Carolina children of ages 2-10 years, and to investigate sources of increased systemic fluoride exposure.
Dietary intake of fluoride ashed (total fluoride) v. unashed (inorganic fluoride) analysis of individual foods
  • D. Taves
  • Medicine
    British Journal of Nutrition
  • 1983
TLDR
Daily fluoride intake was estimated at 1·783 mg which is midway between the 1·211 and 2·201 mg reported from studies in which composite diets were analysed, and a ratio consistent with those previously reported in serum, urine and bone between residents from a non-fluoridated v. fluoridated community.
Renal clearance of fluoride in a steady state condition in man: influence of urinary flow and pH changes by diet.
TLDR
P pH and diuresis both influences fluoride renal clearance, and the results suggests that dietary components as such, influence renal clearance of fluoride in some way or another.
Renal Clearance of Fluoride.∗
TLDR
Fluoride in dog plasma was completely ultrafilterable through visking membranes when tested using the centrifuge type apparatus and the highest ratios were attained during fluoride infusion plus osmotic diuresis with hypertonic mannitol or NaCl.
Fluoride intake from beverage consumption.
TLDR
A substantial source of fluoride was shown to be available in the non-fluoridated community from beverages other than water, primarily from carbonated beverages commercially prepared with fluoridated water.
Determining optimum fluoride concentrations.
TLDR
Results obtained with the equation in the Chicago area, where optimum fluoride concentration is known from epidemiological studies, indicate that it is reasonably reliable and should perhaps be checked by studies in other areas of the country.
Estimation of fluoride absorption from swallowed fluoride toothpastes.
TLDR
Of the toothpastes investigated, the fluoride absorption was found to be statistically significantly lower only from the dicalcium phosphate dihydrate toothpaste, which appears to be an acceptable non-invasive technique for following systemic fluoride absorption.
INGESTION OF FLUORIDE AND DENTAL CARIES: QUANTITATIVE RELATIONS BASED ON FOOD AND WATER REQUIREMENTS OF CHILDREN ONE TO TWELVE YEARS OLD
TLDR
The recent discovery of the inhibitory effect of trace quantities of fluorine in drinking water on dental caries in children aged 12 to 14 years 2 and in young adults 3 marks the first indication that fluorine may have a beneficial role in animal physiology.
...
1
2
3
4
5
...