Intact microtubules support adenovirus and herpes simplex virus infections.

@article{Mabit2002IntactMS,
  title={Intact microtubules support adenovirus and herpes simplex virus infections.},
  author={H{\'e}l{\`e}ne Mabit and Michel Y. Nakano and Ute Prank and Bianca Saam and Katinka D{\"o}hner and Beate Sodeik and Urs F. Greber},
  journal={Journal of virology},
  year={2002},
  volume={76 19},
  pages={9962-71}
}
Capsids and the enclosed DNA of adenoviruses, including the species C viruses adenovirus type 2 (Ad2) and Ad5, and herpesviruses, such as herpes simplex virus type 1 (HSV-1), are targeted to the nuclei of epithelial, endothelial, fibroblastic, and neuronal cells. Cytoplasmic transport of fluorophore-tagged Ad2 and immunologically detected HSV-1 capsids required intact microtubules and the microtubule-dependent minus-end-directed motor complex dynein-dynactin. A recent study with epithelial… CONTINUE READING

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Microtubule-dependent minus and plus end-directed motilities are competing processes for nuclear targeting of adenovirus

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Intact microtubules support adenovirus and herpes simplex virus infections

  • Hélène Nakano Mabit, Y Michel, +4 authors F Urs
  • 2002

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