Int 7 G 24 A Variant of Transforming Growth Factor-B Receptor Type I Is Associatedwith Invasive Breast Cancer

@inproceedings{Chen2006Int7G,
  title={Int 7 G 24 A Variant of Transforming Growth Factor-B Receptor Type I Is Associatedwith Invasive Breast Cancer},
  author={Taiping Chen and Chad R. Jackson and Andrew J. Link and Michael P. Markey and BruceM. Colligan and Larry E. Douglass and Jackson O. Pemberton and James A. Deddens and Jeremy R. Graff and Hannah Carter},
  year={2006}
}
Purpose: The transforming growth factor-h (TGF-h) signaling pathway has been frequently implicated in breast cancer. An intronic variant (Int7G24A) ofTGF-h receptor type I (TGFBR1) is associatedwith kidney andbladder cancers in our recent study.We hypothesize that this germline variant may be involved in development and progression of breast cancer… CONTINUE READING