Insulitis in human diabetes: a histological evaluation of donor pancreases

@inproceedings{Lundberg2016InsulitisIH,
  title={Insulitis in human diabetes: a histological evaluation of donor pancreases},
  author={Marcus Lundberg and Peter Seiron and Sofie Ingvast and Olle Korsgren and Oskar Skog},
  booktitle={Diabetologia},
  year={2016}
}
Aims/hypothesisAccording to the consensus criteria developed for type 1 diabetes, an individual can be diagnosed with insulitis when ≥ 15 CD45+ cells are found within the parenchyma or in the islet–exocrine interface in ≥ 3 islets. The aim of this study was to determine the frequency of individuals with type 2 diabetes fulfilling these criteria with reference to non-diabetic and type 1 diabetic individuals.MethodsInsulitis was determined by examining CD45+ cells in the pancreases of 50, 13 and… CONTINUE READING
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