Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvate carboxykinase, and GLUT4 translocation in experimental diabetic rats.

@article{Anand2010InsulinotropicEO,
  title={Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvate carboxykinase, and GLUT4 translocation in experimental diabetic rats.},
  author={Prachi Anand and Kothandaraman Murali and Vibha Tandon and Pothapragada Suryanarayana Murthy and Ramesh Chandra},
  journal={Chemico-biological interactions},
  year={2010},
  volume={186 1},
  pages={72-81}
}
Diabetes mellitus is a chronic metabolic disorder affecting about 6% of population worldwide with its complications and is rapidly reaching epidemic scale. Cinnamomum zeylanicum is widely used in alternative system of medicine for treatment of diabetes. In the present study, we have performed bioassay guided fractionation of chloroform extract of C. zeylaniucm and identified cinnamaldehyde (CND) as an active principle against diabetes. In continuation to it, a detailed study was undertaken to… CONTINUE READING
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