Insulin use and cancer risk in patients with type 2 diabetes: a systematic review and meta-analysis of observational studies.

@article{Colmers2012InsulinUA,
  title={Insulin use and cancer risk in patients with type 2 diabetes: a systematic review and meta-analysis of observational studies.},
  author={Isabelle N. Colmers and Samantha L. Bowker and Lisa Tjosvold and Jeffrey A. Johnson},
  journal={Diabetes & metabolism},
  year={2012},
  volume={38 6},
  pages={485-506}
}
AIMS To determine whether data from observational studies supports the hypothesis of an increased risk of overall and site-specific cancer among individuals with diabetes using exogenous insulin therapies. METHODS We conducted a comprehensive search of nine key biomedical databases for all years up to December 2011, restricted to the English language. Data from cohort and nested case-control studies were included in random effects meta-analyses of site-specific and overall cancer incidence… CONTINUE READING
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