Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated.

Abstract

Fatty acid oxidation in muscle has been reported to be diminished when insulin and glucose levels are elevated. This study was designed to determine whether activation of AMP-activated protein kinase (AMPK) will prevent inhibitory effects of insulin and glucose on the rate of fatty acid oxidation. Rat hindlimbs were perfused with medium containing 0, 0.3… (More)

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@article{Winder2000InsulinSO, title={Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated.}, author={William Winder and Beulah Holmes}, journal={Journal of applied physiology}, year={2000}, volume={89 6}, pages={2430-7} }