Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle.

@article{Herr2005InsulinstimulatedPM,
  title={Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle.},
  author={Henry J Herr and Jeffrey R. Bernard and Donald W. Reeder and Donato A Rivas and Jose J. Limon and Ben B. Yaspelkis},
  journal={The Journal of physiology},
  year={2005},
  volume={565 Pt 2},
  pages={627-36}
}
Several recent reports using cell lines have suggested that both Akt and atypical protein kinase C (aPKC) zeta/lambda are translocated to the plasma membrane (PM) in response to insulin. However, it has yet to be determined in skeletal muscle whether: (1) insulin increases PM-associated Akt2, aPKC zeta and/or lambda protein concentration, (2) the activity… CONTINUE READING

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