Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase.

@article{Kanai1993InsulinstimulatedGT,
  title={Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase.},
  author={Fumihiko Kanai and Koichi Ito and Mie Todaka and Hisaki Hayashi and Seika Kamohara and Koji Ishii and Taro Okada and Osamu Hazeki and Michio Ui and Y. Ebina},
  journal={Biochemical and biophysical research communications},
  year={1993},
  volume={195 2},
  pages={762-8}
}
We examined the role of 185-kDa insulin receptor substrate-1 (IRS-1) and phosphatidylinositol 3-kinase (PI3-kinase) in the signaling pathway of insulin-stimulated GLUT4 translocation. We had already developed a novel cell line to detect GLUT4 on the cell surface, directly and sensitively (Kanai, F., Nishioka, Y., Hayashi, H., Kamohara, S., Todaka, M., and… CONTINUE READING