Insulin signaling is acutely required for long-term memory in Drosophila

  title={Insulin signaling is acutely required for long-term memory in Drosophila},
  author={Daniel B. Chambers and Alaura Androschuk and Cory S. Rosenfelt and Steven Langer and M. Harding and F. Bolduc},
  journal={Frontiers in Neural Circuits},
  • Daniel B. Chambers, Alaura Androschuk, +3 authors F. Bolduc
  • Published 2015
  • Biology, Medicine
  • Frontiers in Neural Circuits
  • Memory formation has been shown recently to be dependent on energy status in Drosophila. A well-established energy sensor is the insulin signaling (InS) pathway. Previous studies in various animal models including human have revealed the role of insulin levels in short-term memory but its role in long-term memory remains less clear. We therefore investigated genetically the spatial and temporal role of InS using the olfactory learning and long-term memory model in Drosophila. We found that InS… CONTINUE READING
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