Insulin sensitivity in women at risk of coronary heart disease and the effect of a low glycemic diet.

@article{Frost1998InsulinSI,
  title={Insulin sensitivity in women at risk of coronary heart disease and the effect of a low glycemic diet.},
  author={G S Frost and Ashley Leeds and Geoff Trew and Raul A Margara and A. C. Dornhorst},
  journal={Metabolism: clinical and experimental},
  year={1998},
  volume={47 10},
  pages={1245-51}
}
The risk of coronary heart disease (CHD) is influenced by family history, insulin sensitivity (IS), and diet. Adiposity affects CHD and IS. The cellular mechanism of IS is thought to involve the adipocyte cytokine tumor necrosis factor-alpha (TNF-alpha). Insulin-stimulated glucose uptake in isolated subcutaneous and omental adipocytes obtained during elective surgery was measured in 61 premenopausal women, 24 with a parental history (PH) of CHD. In vivo IS was measured using the short insulin… CONTINUE READING
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