Insulin sensitivity in the initial phase of type 1 diabetes mellitus.


The blood glucose response to a brief infusion of insulin (0.012 U/kg body wt) was studied in the initial phase of Type 1 diabetes in 21 children and in 20 healthy controls. The insulin effect was impaired in most of the diabetics and the mean blood glucose decrement was 14.3 +/- 3.5% (SEM) as compared with 20.9 +/- 2.1% in the normals. Subgrouping the… (More)


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