Insulin sensitivity and insulin secretion in monozygotic and dizygotic twins

@article{Lehtovirta2000InsulinSA,
  title={Insulin sensitivity and insulin secretion in monozygotic and dizygotic twins},
  author={Maarit Lehtovirta and Jaakko M Kaprio and Carol Forsblom and J Eriksson and Jaakko Tuomilehto and Leif Groop},
  journal={Diabetologia},
  year={2000},
  volume={43},
  pages={285-293}
}
Aims/hypothesis. To estimate the heritability of insulin sensitivity and insulin secretion, both of which are considered to contribute to the development of Type II (non-insulin-dependent) diabetes mellitus.¶Methods. Intraclass correlation coefficients and heritability estimates for insulin sensitivity (euglycaemic clamp) as well as first-phase and late-phase insulin secretion (intravenous glucose tolerance test) were calculated in 21 monozygotic and 20 dizygotic twin pairs of the same sex… CONTINUE READING
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Methodology for Genetic Studies of Twins and Families

  • MC Neale, LR Cardon
  • NATO ASI Series
  • 1992
Highly Influential
5 Excerpts

Polymor - phism of the human beta 3adrenoreceptor gene forms a wellconserved haplotype that is associated with moderate obesity and altered receptor function

  • J Hoffstedt, O Poirier, A Thorne
  • Diabetes
  • 1999

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