Insulin sensitivity and beta-cell function in protease inhibitor-treated and -naive human immunodeficiency virus-infected children.

@article{Bitnun2005InsulinSA,
  title={Insulin sensitivity and beta-cell function in protease inhibitor-treated and -naive human immunodeficiency virus-infected children.},
  author={Ari S Bitnun and Etienne B. Sochett and Paul T. Dick and Teresa To and Craig Jefferies and Paul Babyn and Jack C Forbes and Stanley E. Read and Susan M. King},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 1},
  pages={168-74}
}
Previous pediatric studies have failed to demonstrate a clear association between protease inhibitor (PI) therapy and abnormal glucose homeostasis in HIV-infected children. To define more precisely the impact of PI therapy on glucose homeostasis in this population, we performed the insulin-modified frequent-sampling iv glucose tolerance test on 33 PI… CONTINUE READING