Insulin-sensitive and insulin-resistant variants in NIDDM.

  title={Insulin-sensitive and insulin-resistant variants in NIDDM.},
  author={Mary Ann Banerji and Harold E. Lebovitz},
  volume={38 6},
To define the sequence of events that is involved in the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM), we studied 16 NIDDM individuals (15 of 16 Black patients) with a mean age of 44 yr who had been near normoglycemic for 2-91 mo while off of antidiabetic medicine. With the euglycemic insulin clamp at 100 microU/ml insulin, we defined two populations, one with normal peripheral insulin sensitivity (glucose disposal 7.51 +/- 0.97 and the other with insulin… CONTINUE READING


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