Insulin secretion in women who have polycystic ovary syndrome and carry the Gly972Arg variant of insulin receptor substrate-1 in response to a high-glycemic or low-glycemic carbohydrate load.

@article{SirPetermann2004InsulinSI,
  title={Insulin secretion in women who have polycystic ovary syndrome and carry the Gly972Arg variant of insulin receptor substrate-1 in response to a high-glycemic or low-glycemic carbohydrate load.},
  author={Teresa Sir-Petermann and B{\'a}rbara Angel and M Manuel Maliqueo and Jos{\'e} Luis Santos and Mar{\'i}a Virginia Riesco and Henry Toloza and Francisco P{\'e}rez-Bravo},
  journal={Nutrition},
  year={2004},
  volume={20 10},
  pages={905-10}
}
OBJECTIVE We evaluated metabolic parameters in Chilean women with polycystic ovary syndrome (PCOS) who were carriers and non-carriers of the glycine-to-arginine substitution at codon 972 (Gly972Arg) variant of insulin receptor substrate-1 and to assess insulin response after oral high- and low-glycemic loads METHODS In 146 women with PCOS and 97 healthy women (HW), Gly972Arg genotypes were obtained by polymerase chain reaction, and an oral glucose tolerance test was performed with glucose and… CONTINUE READING
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