Insulin secretion in fetal and newborn sheep.

  title={Insulin secretion in fetal and newborn sheep.},
  author={Anthony F. Philipps and Bonita S Carson and Giacomo Meschia and Frederick C. Battaglia},
  journal={The American journal of physiology},
  volume={235 5},
The relationships between arterial plasma insulin, glucose, and fructose concentrations during the fed and fasted state were studied in seven fetal lambs and their mothers. A significant correlation between insulin and glucose concentration was noted in all fetal lambs and in their mothers. Fetal sensitivity to glucose, as measured by the slopes of the insulin-response curves, was equal to that of the adult although the fetal response was shifted to the left of the maternal. Glucose infusion in… CONTINUE READING