Insulin-responsive aminopeptidase trafficking in 3T3-L1 adipocytes.

@article{Garza2000InsulinresponsiveAT,
  title={Insulin-responsive aminopeptidase trafficking in 3T3-L1 adipocytes.},
  author={Luis A. Garza and Morris J Birnbaum},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 4},
  pages={2560-7}
}
The insulin-responsive aminopeptidase (IRAP/VP165/gp160) was identified originally in GLUT4-containing vesicles and shown to translocate in response to insulin, much like the glucose transporter 4 (GLUT4). This study characterizes the trafficking and kinetics of IRAP in exocytosis, endocytosis, and recycling to the membrane in 3T3-L1 adipocytes. After exposure of 3T3-L1 adipocytes to insulin, IRAP translocated to the plasma membrane as assessed by either cell fractionation, surface… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.

23323–23327 IRAP Trafficking in 3T3-L1 Adipocytes

  • S. B. Waters, M. D’Auria, S. S. Martin, C. Nguyen, L. M. Kozma, K. L. Luskey
  • J. Biol. Chem
  • 1997

Similar Papers

Loading similar papers…