Insulin resistance in polycystic ovary syndrome.

  title={Insulin resistance in polycystic ovary syndrome.},
  author={Gordana M Prelevic},
  journal={Current opinion in obstetrics & gynecology},
  volume={9 3},
Hyperinsulinaemia is found in 30% of slim and 75% of obese women with polycystic ovary syndrome. Despite resistance to insulin action in terms of glucose transport, increased insulin levels may cause hyperandrogenaemia by enhancement of androgen production in the ovaries where insulin acts as co-gonadotrophin. Recent interest in insulin resistance results from the recognition that it predisposes to various metabolic abnormalities, and could be involved in the pathogenesis of atherosclerosis… CONTINUE READING