Insulin resistance in obesity as analyzed by the response of glucose kinetics to glucagon infusion.

@article{Vranic1980InsulinRI,
  title={Insulin resistance in obesity as analyzed by the response of glucose kinetics to glucagon infusion.},
  author={Mladen Vranic and Seiichi Morita and George Steiner},
  journal={Diabetes},
  year={1980},
  volume={29 3},
  pages={169-76}
}
A new approach has been developed to examine insulin sensitivity and resistance in vivo in man. In it, tracer methods are used, which permit the assessment of nonsteady state glucose kinetics by a method that is noninvasive and does not use pharmacologic agents. Graded doses of glucagon, infused intravenously, are used to drive glucose out of steady state… CONTINUE READING