Insulin resistance during puberty: results from clamp studies in 357 children.

@article{Moran1999InsulinRD,
  title={Insulin resistance during puberty: results from clamp studies in 357 children.},
  author={Antoinette Moran and David R. Jacobs and Julia K. Steinberger and C P Hong and Ronald J. Prineas and Russell B. Luepker and Alan Sinaiko},
  journal={Diabetes},
  year={1999},
  volume={48 10},
  pages={2039-44}
}
Insulin resistance may be an important cause of a constellation of cardiovascular risk factors in adults, and onset of this syndrome may occur in childhood. However, children normally experience transient insulin resistance at puberty. There were 357 normal children (159 girls, 198 boys) age 10-14 years who underwent euglycemic clamp studies to assess the effects of Tanner stage (T), sex, ethnicity, and BMI on insulin resistance. Insulin resistance increased immediately at the onset of puberty… CONTINUE READING