Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides.

@article{Manco2000InsulinRD,
  title={Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides.},
  author={Melania Manco and Geltrude Mingrone and A. V. Greco and Esmeralda Capristo and Donatella Gniuli and Andrea de Gaetano and Giovanni Battista Gasbarrini},
  journal={Metabolism: clinical and experimental},
  year={2000},
  volume={49 2},
  pages={220-4}
}
A close relationship between elevated plasma free fatty acid (FFA) levels and insulin resistance is commonly reported in obese subjects. The aim of the present study was to evaluate the role of intramuscular triglyceride (mTG) and FFA levels in insulin sensitivity in 30 nondiabetic normal-weight or obese subjects (18 with body mass index [BMI] = 21.8 +/- 3.3 kg/m2 and 12 with BMI = 34.6 +/- 2.7 kg/m2) who underwent minor abdominal surgery. Body composition was estimated by isotopic dilution… CONTINUE READING

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