Insulin resistance and upper-normal glucose levels in hypertension: a review

@article{Cubeddu2002InsulinRA,
  title={Insulin resistance and upper-normal glucose levels in hypertension: a review},
  author={Luigi X. Cubeddu and Irene S. Hoffmann},
  journal={Journal of Human Hypertension},
  year={2002},
  volume={16},
  pages={S52-S55}
}
Reduced insulin-mediated glucose disposal, indicative of insulin resistance, has been demonstrated in lean male hypertensives both with the hyperinsulinaemic euglycaemic clamp and the insulin suppression test. In lean hypertensives, insulin resistance was not accompanied by increases in fasting plasma insulin and glucose levels; but with modest hyperglycaemia and hyperinsulinaemia after a glucose load. Population studies (no stratification) reveal that: (1) insulin sensitivities vary widely in… CONTINUE READING

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