Insulin resistance and systemic inflammation, but not metabolic syndrome phenotype, predict 9 years mortality in older adults.

@article{Zuliani2014InsulinRA,
  title={Insulin resistance and systemic inflammation, but not metabolic syndrome phenotype, predict 9 years mortality in older adults.},
  author={Giovanni Zuliani and Mario Luca Morieri and Stefano Volpato and Marcello Giuseppe Maggio and Antonio Cherubini and Daniela Francesconi and Stefania Bandinelli and Guiseppe Paolisso and Jack Guralnik and Luigi Ferrucci},
  journal={Atherosclerosis},
  year={2014},
  volume={235 2},
  pages={538-45}
}
BACKGROUND Although metabolic syndrome (MS) is a typical condition of middle-aged/older person, the association between MS and mortality risk has not been confirmed in people over 65 years. We hypothesized that while in the elderly MS phenotype might lose its value in predicting mortality risk, the two core factors of MS, i.e. insulin resistance (IR) and low grade systemic inflammation (LGSI) would not. METHODS 1011 community-dwelling older individuals (InCHIANTI study) were included. MS… CONTINUE READING
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