Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes.

@article{Perseghin2003InsulinRI,
  title={Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes.},
  author={Gianluca Perseghin and Guido Lattuada and Massimo Danna and Lucia Piceni Sereni and Paola Maffi and Francesco de Cobelli and Alberto Battezzati and Antonio Secchi and Alessandro Del maschio and Livio Luzi},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2003},
  volume={285 6},
  pages={E1174-81}
}
Insulin resistance is a key pathogenic factor of type 2 diabetes (T2DM); in contrast, in type 1 diabetes (T1DM) it is considered a secondary alteration. Increased intramyocellular lipid (IMCL) content accumulation and reduced plasma adiponectin were suggested to be pathogenic events of insulin resistance in T2DM. This study was designed to assess whether… CONTINUE READING