Insulin resistance, apoptosis, and colorectal adenoma risk.

@article{Keku2005InsulinRA,
  title={Insulin resistance, apoptosis, and colorectal adenoma risk.},
  author={Temitope O. Keku and Pauline Kay Lund and Joseph Galanko and James G. Simmons and John T. Woosley and Robert S. Sandler},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2005},
  volume={14 9},
  pages={
          2076-81
        }
}
Compelling evidence from epidemiologic studies indicates that elevated circulating insulin-like growth factor (IGF)-I, insulin resistance, and associated complications, such as elevated fasting plasma insulin, glucose and free fatty acids, glucose intolerance, increased body mass index, and visceral adiposity, are linked with increased risk of colorectal cancer. However, the role of insulin and markers of glucose control in the development of adenomas, precursors to colorectal cancer, has not… CONTINUE READING

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