Insulin potentiates cytokine-induced VCAM-1 expression in human endothelial cells.

Abstract

Hyperinsulinemia is an independent risk factor for cardiovascular events and may contribute to cardiovascular disease. Low-grade chronic inflammation has been implicated in the pathogenesis of atherosclerosis. We aimed at determining the impact of pathophysiologically high insulin concentrations on cytokine-induced endothelial activation in human umbilical… (More)
DOI: 10.1016/j.bbadis.2008.05.006

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