Insulin modulates network activity in olfactory bulb slices: impact on odour processing.

@article{Kuczewski2014InsulinMN,
  title={Insulin modulates network activity in olfactory bulb slices: impact on odour processing.},
  author={Nicola Kuczewski and Nicolas Fourcaud-Trocm{\'e} and Agn{\`e}s Savigner and M. Th{\'e}venet and Pascaline Aim{\'e} and Samuel Garcia and Patricia Duchamp-Viret and Brigitte Palouzier-Paulignan},
  journal={The Journal of physiology},
  year={2014},
  volume={592 13},
  pages={2751-69}
}
Odour perception depends closely on nutritional status, in animals as in humans. Insulin, the principal anorectic hormone, appears to be one of the major candidates for ensuring the link between olfactory abilities and nutritional status, by modifying processing in the olfactory bulb (OB), one of its main central targets. The present study investigates whether and how insulin can act in OB, by evaluating its action on the main output neurons activities, mitral cells (MCs), in acute rat OB… CONTINUE READING
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