Insulin-like growth factors and insulin: comparative aspects

@article{Froesch1985InsulinlikeGF,
  title={Insulin-like growth factors and insulin: comparative aspects},
  author={E. Rudolf Froesch and Juergen Zapf},
  journal={Diabetologia},
  year={1985},
  volume={28},
  pages={485-493}
}
IGF I and IGF II are two insulin-like growth factors resembling insulin in many respects. They stem from a common precursor, act through receptors similar to the insulin receptor with which they cross-react. When administered in large amounts they produce hypoglycemia. Their major effects, however, are on replication and differentiation of cells of mesodermal origin. IGF I is the major growth promoting factor in vivo. The synthesis and secretion of IGF I by the liver depend on the growth… CONTINUE READING

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Insulin - like growth factor I and growth hormone in canine starvation

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  • Acta Endocrinol ( Kbh )
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Insulin-like growth factor I and II in 13 animal species as determined by three radioligand- and two bioassays

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  • Acta Endocrinol (Kbh)
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Froesch ER (1984) Body size paral- lels insulin-like growth factor I levels but not growth hormone se- cretory capacity

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  • 1984
3 Excerpts

Insulin-like growth fac tor I supports differentiation of cultured osteoblast-like cells

  • Schmid Ch, Steiner Th, ER Froesch
  • Febs Lett 173:48-52
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