Insulin-like growth factors and breast cancer risk in Chinese women.

  title={Insulin-like growth factors and breast cancer risk in Chinese women.},
  author={Herbert Yu and Fan Jin and Xiao-ou Shu and Benjamin D. L. Li and Qi Dai and Jia-rong Cheng and Hans J. Berkel and Wei Zheng},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  volume={11 8},
Insulin-like growth factor (IGF)-I has mitogenic and antiapoptotic effects on breast cancer cells. High-circulating IGF-I was found to be associated with increased risk of breast cancer in several previous epidemiological studies, mostly conducted in the Caucasian populations. Little is known about the association between IGF and breast cancer in Asian women whose dietary habits differ considerably from their Caucasian counterparts. A population-based case-control study was conducted to assess… CONTINUE READING