Insulin-like growth factor ligands, receptors, and binding proteins in cancer.

@article{Foulstone2005InsulinlikeGF,
  title={Insulin-like growth factor ligands, receptors, and binding proteins in cancer.},
  author={Emily J. Foulstone and Sharon Prince and Oliver J Zaccheo and Jason L Burns and Jane Harper and Corbin D Jacobs and Diane Church and Andrew B. Hassan},
  journal={The Journal of pathology},
  year={2005},
  volume={205 2},
  pages={145-53}
}
This review aims to summarize experimental evidence supporting the role of the insulin-like growth factor (IGF) signalling system in the progression, maintenance, and treatment of cancer. These data implicate the IGF system as an important modifier of cancer cell proliferation, survival, growth, and treatment sensitivity. The role of the IGF system in… CONTINUE READING