Insulin-like growth factor-binding protein-1 and prostate cancer.

@article{Signorello1999InsulinlikeGF,
  title={Insulin-like growth factor-binding protein-1 and prostate cancer.},
  author={Lisa B. Signorello and Kerstin E Brismar and R R Bergstrom and S. O. Andersson and Alicja Wolk and Dimitirios Trichopoulos and Hans Olov Adami},
  journal={Journal of the National Cancer Institute},
  year={1999},
  volume={91 22},
  pages={1965-7}
}
There is growing and persuasive evidence, both experimental (1–4) and epidemiologic (5–7), that the peptide hormone insulin-like growth factor-I (IGF-I) is a critical factor in the development of prostate cancer. Because of their central role in the regulation of bioavailable IGF-I, the insulin-like growth factor-binding proteins (IGFBPs) have also come under scrutiny as potential mediators of prostate cancer risk (8–12). There is considerable disagreement concerning which, if any, of the… CONTINUE READING

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References

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Showing 1-10 of 25 references

Differential expression of insulin - like growth factor binding proteins in high versus low Gleason score prostate can

  • JA Figueroa, S DeRaad, L Tadlock, VO Speights, JJ Rinehart
  • J Urol
  • 1998

Insulin-like growth

  • PJ Ho, RC Baxter
  • cer. J Urol 1998;159:1379–83
  • 1998

proteases. Endocrine 1997;7:115–8

  • JI Jones, DR Clemmons
  • 1997

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