Insulin-like growth factor-II enhancement of human fibroblast growth via a nonreceptor-mediated mechanism.

@article{Conover1994InsulinlikeGF,
  title={Insulin-like growth factor-II enhancement of human fibroblast growth via a nonreceptor-mediated mechanism.},
  author={Cheryl A. Conover and Jacquelyn Clarkson and Laurie K. Bale},
  journal={Endocrinology},
  year={1994},
  volume={135 1},
  pages={76-82}
}
Deciphering the complex interactions of the various components of the insulin-like growth factor (IGF) system [IGF-I and -II peptides, type I and II IGF receptors, and IGF-binding proteins (IGFBPs)] is important for our understanding of cell growth regulation. We report here that IGF-II can enhance IGF-I-stimulated cell proliferation independent of direct… CONTINUE READING