Insulin-like growth factor-I induces phosphorylation in Leishmania (Leishmania) mexicana promastigotes and amastigotes.

@article{Gomes1998InsulinlikeGF,
  title={Insulin-like growth factor-I induces phosphorylation in Leishmania (Leishmania) mexicana promastigotes and amastigotes.},
  author={Cristiano Mendes Gomes and Hugo P Monteiro and Magnus Gidlund and Carlos Eduardo Pereira Corbett and Hiro Goto},
  journal={The Journal of eukaryotic microbiology},
  year={1998},
  volume={45 3},
  pages={352-5}
}
Protein phosphorylation controls major steps of proliferation and differentiation in eukaryotic cells. However there are few studies done in protozoa particularly when being triggered by external stimuli. In this paper we have examined the tyrosine- and serine/threonine-phosphorylated proteins in both promastigote and amastigote-like forms of Leishmania (Leishmania) mexicana stimulated with insulin-like growth factor (IGF)-I. Stimulation with IGF-I induces major tyrosine phosphorylation of a… CONTINUE READING

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