Insulin-like growth factor 2 (IGF2 ) and IGF-binding protein 1 (IGFBP1) gene variants are associated with overfeeding-induced metabolic changes

@article{Ukkola2001InsulinlikeGF,
  title={Insulin-like growth factor 2 (IGF2 ) and IGF-binding protein 1 (IGFBP1) gene variants are associated with overfeeding-induced metabolic changes},
  author={Olavi H Ukkola and Gao Sun and Claude Bouchard},
  journal={Diabetologia},
  year={2001},
  volume={44},
  pages={2231-2236}
}
The aim of this study was to investigate the role of insulin-like growth factor 1 (IGF1), IGF2, IGF binding protein 1 (IGFBP1) and IGFBP3 gene variants on the metabolic changes observed in response to a 100-day overfeeding protocol conducted with 12 pairs of monozygotic twins. Genotyping was done by PCR-RFLP and DNA sequencer methods. Body fat measurements… CONTINUE READING