Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort

@inproceedings{Miyake2013InsulinlikeGF,
  title={Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort},
  author={Masahiro Miyake and Kenji Yamashiro and Hideo Nakanishi and Isao Nakata and Yumiko Akagi-Kurashige and Akitaka Tsujikawa and Muka Moriyama and Kyoko Ohno-Matsui and Manabu Mochizuki and Ryo Yamada and Fumihiko Matsuda and Nagahisa Yoshimura},
  booktitle={Molecular vision},
  year={2013}
}
PURPOSE To investigate whether genetic variations in the insulin-like growth factor 1 (IGF-1) gene are associated with high myopia in Japanese. METHODS A total of 1,339 unrelated Japanese patients with high myopia (axial length ≥26 mm in both eyes) and two independent control groups were evaluated (334 cataract patients without high myopia and 1,194 healthy Japanese individuals). The mean axial length (mm±SD) in the case group was 29.18±1.85 mm, and the mean spherical equivalent (D±SD) of the… CONTINUE READING

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