Insulin-like Growth Factor-i (igf-i) Potentiates Lh-induced Stimulation of Androgen Synthesis by Rat Ovarian Theca-interstitial (ti) Cells


We tested the hypothesis that IGF-I plays a role in ovarian TI cell cytodifferentiation.Dispersed TI cells obtained from 21 day old hypox Sprague Dawley rats were cultured in serum-free medium in the absence and presence of increasing concentrations of LH, IGF-I or a combination of these hormones. The culture medium was changed every 48 hours and the… (More)
DOI: 10.1203/00006450-198704010-00466


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