Insulin-like Growth Factor Binding Protein 3 (igfbp-3) Concentration in Cerebrospinal Fluid (csf) of Children with Brain Tumors or Leukemia

@article{Mller1993InsulinlikeGF,
  title={Insulin-like Growth Factor Binding Protein 3 (igfbp-3) Concentration in Cerebrospinal Fluid (csf) of Children with Brain Tumors or Leukemia},
  author={Hermann L M{\"u}ller and Y. L. Oh and Sharron E. Gargosky and R L Ilintz and Ron G. Rosenfeld},
  journal={Pediatric Research},
  year={1993},
  volume={33},
  pages={S41-S41}
}
The major IGFBPs in CSF are IGFBP-2 and IGFBP-4. whereas IGFBP-3 is a minor component in CSF of healthy subjects. We investigated IGFBP-3 levels in CSF from patients with brain tumors, leukemia or meningitis. IGFBP-3 was measured by radioimmuno-assay with αIGFBP-3g I, a rabbit polyclonal antibody. Further, as proteolysis of IGFBP-3 is purt of the modulation… CONTINUE READING